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Developers:
Themes:
Everyone likes to see content in a lightbox these days. So this is a pretty extensive dive into the lightbox scripts available out there.  FYI - a select few have been left out because they are based on existing scripts with no real difference or were flash-based. And believe it or not, I haven't even dug into the lightbox addons from RW developers - Would this be something you would like to see?

Let me know if this kind of general info is helpful, as research and fact gathering is well, time consuming to say the least ;)

Bumpbox

  • Supports: Image, Image Sets, Inline HTML, PDF, iFrame, FLV, Flash, Audio, YouTube, Vimeo
  • Functionality: Dynamic frame resizing, Title, Image Resizing
  • Scripts: MooTools

CeeBox

  • Supports: Image, Image Sets, Inline HTML, AJAX, iFrame, Videos, Flash
  • Functionality: Smooth frame resizing, Title
  • Scripts: jQuery

CeraBox

  • Supports: Image, Image Sets, Inline HTML, AJAX, iFrame, Flash, Video
  • Functionality: Dynamic frame resizing, Title, Image Resizing, Mobile support
  • Scripts: MooTools

ColorBox

  • Supports: Image, Image Sets, Inline HTML, AJAX, iFrame
  • Functionality: Smooth frame resizing, Title, Image Resizing, Slideshow
  • Scripts: jQuery

Control.Modal

  • Supports: Image, Inline HTML, AJAX, iFrame
  • Functionality: Title, Frame Draggable
  • Scripts: Prototype

easyAlbum

  • Supports: Image, Image Sets
  • Functionality: Title, Caption
  • Scripts: Standard Javascript

EasyBox

  • Supports: Image, Image Sets, Inline HTML, YouTube, Vimeo, iFrame
  • Functionality: Smooth frame resizing, Title, Image Resizing, Slideshow
  • Scripts: jQuery

EnlargeIt!

  • Supports: Image, Image Sets, AJAX, iFrame, Flash, FLV, YouTube, DivX
  • Functionality: Dynamic frame zoom, Title, Multiple images at once
  • Scripts: Standard Javascript

Fancybox

  • Supports: Image, Image Sets, Flash, Inline HTML, iFrame, AJAX
  • Functionality: Smooth frame resizing, Outer/Std/Overlay Caption, Overlay nav buttons
  • Scripts: jQuery

Fancy Zoom (jQuery)

  • Supports: Image, Inline HTML, Flash
  • Functionality: Smooth frame resizing, Caption
  • Scripts: Protoype or jQuery

Floatbox

  • Commercial: $20
  • Supports: Image, Image Sets, Inline HTML, PDF, AJAX, iFrame, Flash, YouTube, Vimeo, DailyMotion, QuickTime
  • Functionality: Smooth frame resizing, Title, Caption, Slideshow, Mobile support
  • Scripts: Standard Javascript

Galleria

  • Supports: Image, Image Sets, Inline HTML, iFrame, AJAX, Flickr, Picasa
  • Functionality: Image Resizing, Automatic Thumbnail Navigation, Title, Caption, Loop, Slideshow, Slideshow Loop, Mobile support
  • Scripts: jQuery

GreyBox

  • Supports: Image, Image Sets, iFrame
  • Functionality: Static frame resizing, Caption
  • Scripts: AJS

Highslide

  • Commercial: $29
  • Supports: Image, Image Sets, Inline HTML, AJAX, iFrame, Flash, YouTube
  • Functionality: Dynamic frame zoom, Caption, Slideshow
  • Scripts: Standard Javascript

Imagebox

  • Supports: Image, Image Sets
  • Functionality: Smooth frame resizing, Title
  • Scripts: jQuery

ImageZoom

  • Supports: Image, Image Sets
  • Functionality: Dynamic frame zoom, Title, Frame Draggable
  • Scripts: MooTools

Lightbox/Lightbox2/Lightbox JS

  • Supports: Image, Image Sets
  • Functionality: Smooth frame resizing, Caption, Overlay nav buttons
  • Scripts: Prototype & Scriptaculous

Lightbox+

  • Supports: Image, Image Sets
  • Functionality: Smooth frame resizing, Title, Expandable Image, Frame Draggable
  • Scripts: Standard Javascript

Lightbox Evolution

  • License: $12
  • Supports: Image, Image Sets, Inline HTML, Flash, YouTube, Vimeo, Metacafe, DailyMotion, Google Videos, TwitVid, Maps
  • Functionality: Smooth frame resizing, Caption, Image Resizing, Loop, 7 Themes
  • Scripts: jQuery

Lightview

  • Non-Commercial: 3GBP, Comercial: 49GBP
  • Supports: Image, Image Sets, Inline HTML, AJAX, iFrame, QuickTime, Flash
  • Functionality: Smooth frame resizing, Title
  • Scripts: Prototype & Scriptaculous

LightWindow

  • Supports: Image, Image Sets, Inline HTML, iFrame, PDF, Flash, YouTube, AJAX
  • Functionality: Smooth frame resizing, Caption, Title, Overlay Nav Buttons, Author
  • Scripts: Prototype & Scriptaculous

Lytebox

  • Supports: Image, Image Sets, iFrame, Inline HTML, Flash, PDF, YouTube, DailyMotion, QuickTime
  • Functionality: Smooth frame resizing, Title, Caption, Slideshow, Slideshow Loop
  • Scripts: Standard Javascript

mediaboxAdvanced (Mediabox Standard deprecated)

  • Supports: Image, Image Sets, Inline HTML, iFrame, Twitter media, Social Video, Audio, Flash, QuickTime, YouTube, Vimeo
  • Functionality: Smooth frame resizing, Title, Caption
  • Scripts: MooTools

Milkbox

  • Supports: Image, Image Sets, iFrame, Flash
  • Functionality: Smooth frame resizing, Caption, Image Resizing, Loop
  • Scripts: MooTools

minishowcase

  • Supports: Image, Image Sets, AJAX
  • Functionality: Automatic Thumbnail Navigation, Static frame resizing, Title, Image Resizing
  • Scripts: PHP

Multifaceted Lightbox

  • Supports: Image, Inline HTML, AJAX
  • Functionality: Basic
  • Scripts: Prototype

nyroModal

  • Supports: Image, Image Sets, Inline HTML, AJAX, iFrame, YouTube
  • Functionality: Smooth frame resizing, Title, Image Resizing, Loop
  • Scripts: jQuery

piroBox

  • Supports: Image, Image Sets, Inline HTML, Flash, PDF, YouTube, Vimeo
  • Functionality: Smooth frame resizing, Title, Image Resizing, 4 Themes, Expandable Image
  • Scripts: jQuery

prettyPhoto

  • Supports: Image, Image Sets, Inline HTML, iFrame, Flash, YouTube, Vimeo, QuickTime
  • Functionality: Smooth frame resizing, Title, Caption, Overlay nav buttons, Thumbnail Nav, Nav Looping, 5 Themes
  • Scripts: jQuery

qGallery

  • Supports: Image, Image Sets
  • Functionality: Smooth frame resizing, Image Resizing, Automatic Thumbnail Navigation, Caption, Loop
  • Scripts: Prototype

Satellite

  • Supports: Image, Image Sets, Flickr
  • Functionality: Title
  • Scripts: PHP

Shadowbox

  • Commercial license-$20USD (Unlimited domains)
  • Supports: Image, Image Sets, Inline HTML, iFrame, Flash, YouTube, Yahoo, Vimeo, Google, QuickTime, Windows Media
  • Functionality: Smooth frame resizing, Caption, Nav Looping, Image Resize
  • Scripts: Prototype or MooTools or jQuery or Dojo or Yahoo or Ext

Slideshow 2!

  • Supports: Image, Image Sets
  • Functionality: Smooth frame resizing, Image Resizing, Automatic Thumbnail Navigation, Caption, Slideshow, Slideshow Loop
  • Scripts: MooTools

SlideWindow

  • Supports: Image, Image Sets
  • Functionality: Title
  • Scripts: Standard Javascript

Slimbox

  • Supports: Image, Image Sets, Inline HTML
  • Functionality: Smooth frame resizing, Caption, Overlay nav buttons, Nav Looping
  • Scripts: MooTools or jQuery

Suckerfish HoverLightbox Redux

  • Supports: Image, Image Sets
  • Functionality: Title
  • Scripts: Prototype + Scriptaculous

Thickbox

  • Supports: Image, Image Sets, Inline HTML, iFrame, AJAX
  • Functionality: Static frame resizing, Title, Image Resizing
  • Scripts: jQuery

tinyLightbox

  • Supports: Image, Image Sets
  • Functionality: Smooth frame resizing, Caption, Slideshow, Slideshow Loop
  • Scripts: jQuery

TopUp

  • Supports: Image, Image Sets, Inline HTML, iFrame, AJAX, Flash, YouTube, FLV, QuickTime, Video
  • Functionality: Smooth frame resizing, Title, Image Resizing, Frame Draggable, Frame Adjustable, 2 Themes
  • Scripts: jQuery + jQuery UI

TripTracker

  • Supports: Image, Image Sets, Inline HTML, iFrame, AJAX, Flash, YouTube, FLV, QuickTime, Video
  • Functionality: Static frame resizing, Title, Byline, Slideshow, Slideshow Loop, Image Pan
  • Scripts: Standard Javascript

Videobox

  • Supports: Flash, YouTube, Google, Metacafe, iFilm
  • Functionality: Smooth frame resizing, Caption
  • Scripts: MooTools

Visual Lightbox JS

  • Commercial: $49
  • Supports: Image, Image Sets, Photobucket, Flickr
  • Functionality: Smooth frame resizing, Title, Caption, 18 Themes, Image Resizing, Watermarks, Slideshow
  • Scripts: jQuery or Prototype + Scriptaculous

YUI lightbox

  • Supports: Image
  • Functionality: Title, Image Resizing, Expandable Image, Frame Draggable
  • Scripts: YUI
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